The CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats)/ Cas9 (CRISPR-associated protein 9) system enables scientists to edit diverse genome types with relative ease, with the aim – in the near future – to prevent future human beings from developing genetic diseases. The new opportunities arising from the system are broad-ranging and revolutionary, but such prospects have also been the cause for alarm throughout the international scientific community. The authors have laid out a review of the trials carried out so far in terms of genome editing, for the ultimate purpose of weighing implications and criticisms. We feel that possible valuable alternatives, such as induced pluripotent stem cells should not be overlooked.

Commentary – CRISPR-based techniques: Cas9, Cas13 and their applications in the era of COVID-19 / Zaami, S.; Piergentili, R.; Marinelli, E.; Montanari Vergallo, G.. - In: EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES. - ISSN 1128-3602. - 25:3(2021), pp. 1752-1761. [10.26355/eurrev_202102_24886]

Commentary – CRISPR-based techniques: Cas9, Cas13 and their applications in the era of COVID-19

Zaami S.
Primo
;
Piergentili R.;Marinelli E.
Penultimo
;
Montanari Vergallo G.
Ultimo
2021

Abstract

The CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats)/ Cas9 (CRISPR-associated protein 9) system enables scientists to edit diverse genome types with relative ease, with the aim – in the near future – to prevent future human beings from developing genetic diseases. The new opportunities arising from the system are broad-ranging and revolutionary, but such prospects have also been the cause for alarm throughout the international scientific community. The authors have laid out a review of the trials carried out so far in terms of genome editing, for the ultimate purpose of weighing implications and criticisms. We feel that possible valuable alternatives, such as induced pluripotent stem cells should not be overlooked.
2021
CRISPR/Cas9-Cas13; Enhancement; Germline gene editing; Human embryo research; Sars-CoV-2; CRISPR-Associated Protein 9; CRISPR-Associated Proteins; Gene Editing; Genetic Therapy; Humans; SARS-CoV-2; COVID-19; CRISPR-Cas Systems; Clustered Regularly Interspaced Short Palindromic Repeats
01 Pubblicazione su rivista::01a Articolo in rivista
Commentary – CRISPR-based techniques: Cas9, Cas13 and their applications in the era of COVID-19 / Zaami, S.; Piergentili, R.; Marinelli, E.; Montanari Vergallo, G.. - In: EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES. - ISSN 1128-3602. - 25:3(2021), pp. 1752-1761. [10.26355/eurrev_202102_24886]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1540272
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